摘要

Sjogren syndrome (SS) is a gradual and progressive autoimmune disease characterized by the lymphocytic and plasma cell infiltration of exocrine glands such as lacrimal and salivary glands. It is estimated that the worldwide incidence of SS is 7 per 100,000 people, with the highest incidence rates in Europe and Asia, reaching up to 43 per 100,000 people.1 Lacrimal gland involvement in SS often leads to aqueous deficient dry eye, which is classically associated with a marked decrease in tear production and severe ocular surface inflammation. Dry eye associated with SS is often more severe than non-SS dry eye. Nevertheless, the pathogenesis of dry eye in SS is poorly understood because lacrimal gland biopsy is relatively invasive compared with that of the minor salivary glands.  译干燥综合征(ssogren syndrome,SS)是一种渐进性的自身免疫性疾病,以泪腺和唾液腺等外分泌腺的淋巴细胞和浆细胞浸润为特征。据估计,全世界SS发病率为7/10万,欧洲和亚洲发病率最高,高达43/10万,1泪腺参与SS常导致缺水性干眼症,与泪液分泌明显减少和严重眼表炎症有关。与SS相关的干眼症通常比非SS干眼症更严重。然而,由于泪腺活检与小涎腺活检相比具有相对的侵袭性,对SS干眼症的发病机制了解甚少。

译文

干燥综合征(ssogren syndrome,SS)是一种渐进性的自身免疫性疾病,以泪腺和唾液腺等外分泌腺的淋巴细胞和浆细胞浸润为特征。据估计,全世界SS发病率为7/10万,欧洲和亚洲发病率最高,高达43/10万,1泪腺参与SS常导致缺水性干眼症,与泪液分泌明显减少和严重眼表炎症有关。与SS相关的干眼症通常比非SS干眼症更严重。然而,由于泪腺活检与小涎腺活检相比具有相对的侵袭性,对SS干眼症的发病机制了解甚少。

Sjogren Syndrome (SS)

免疫 干燥综合征 疾病
概述  :  

干燥综合征,是一种以侵犯泪腺、唾液腺等外分泌腺为主的慢性自身免疫性疾病,又称为自身免疫性外分泌腺体病。可累及其他系统如呼吸系统、消化系统、泌尿系统、血液系统、神经系统以及肌肉、关节等造成多系统、多器官受损。本病可以单独存在,亦可出现在其他自身免疫病中,单独存在者为原发性干燥综合征,而继发于类风湿性关节炎、系统性硬皮病、系统性红斑狼疮等其他自身免疫病者为继发性干燥综合征。本病发病率高,多发于 40 岁以上女性。 病因 1.自身免疫:干燥综合征

Sjogren

释义    n. (Sjogren)人名;(英)肖格伦

例句    Persistent dry eyes. Any condition that causes dry eyes, including the autoimmune disease Sjogren's syndrome, is likely to impair healing.包括自体免疫性疾病干燥综合征(Sjogren's syndrome),任何引起眼睛干燥的情形都可能损害康复。

 

Syndrome   英 /ˈsɪndrəʊm/ 美 /ˈsɪndroʊm/

释义    n. [临床] 综合征;综合症状

例句    But now the condition, also called "toasted skin syndrome", is being seen in some laptop users. 但现在的状况,也叫“烤皮肤综合征”,正出现在一些笔记本电脑用户中。

请扫描右侧二维码,免费查看词汇专业知识背景